In Vitro Services and Tumor Immunophenotyping
We offer a full suite of in vitro services for the assessment of novel ocular and oncology therapeutics, including tumor immunophenotyping and cellular assay development.
As a specialized preclinical CRO, our scientists rapidly pilot and optimize assays with flexibility and precision to support ocular drug development, immuno-oncology research, and preclinical R&D programs.
Services Available:
Front-to-Back Tissue Processing:
• Cell/organ harvest and fixation
• Paraffin embedding and cryopreservation
• Flat mounts
• Sectioning and staining
Histopathology
Immunohistochemistry
Immunofluorescence
RNAscope in situ hybridization
Fluorescence microscopy
Light microscopy
Fluorescence live imaging
Image analysis and quantification
Cytokine analysis
Genotyping
qPCR
ELISA
Western blotting
Cell culture (BSL2)
Flow cytometry
Ocular Specialization
Histological stains and antibodies for diagnostic and marker-based analyses including:
Histopathology
H&E | Masson’s Trichrome | Periodic Acid-Schiff
Immunohistochemistry & Immunofluorescence Rhodopsin | RPE65 | Laminin | TUJ-1 | IBA-1 | PNA Lectin | Phalloidin | Luciferase | GFP | RBPMS Complement family antibodies and fibrotic markers
In-House In Vitro Services = Speed + Control
Mouse Cornea
Rabbit Retina
Mouse Retina
Mouse Cornea
Rabbit Cornea
Rabbit Retina
Mouse Flat Mount
Rat Flat Mount
Stain legend: Cone arrestin: cone cells; Rhodopsin: rod cells; PNA Lectin: photoreceptors; TUJ1: neurons; Phalloidin: F-actin; IBA1: microglia; Isolectin IB4: vasculature.
Tumor Immunophenotyping and Cytokine Analysis
We offer a comprehensive suite of standard and custom tumor immunophenotyping panels and cytokine arrays. Our scientists excel at piloting and optimizing new techniques and processes with flexibility, speed, and resourcefulness, ensuring reproducibility and tailored solutions to advance your preclinical R&D programs.
Services Available:
Tissue Processing:
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Cell/organ harvest and fixation
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Cell isolation
Flow Cytometry
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Full-spectrum Cytek® Aurora flow cytometer with automated sample loader
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Immunophenotyping of a variety of tissues (e.g., blood, spleen, and tumor)
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Standard and custom panel designs with 18+ color options
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Cytokine analysis of serum/plasma and tumor lysates
Tumor T-Lymphocyte Populations
Reproducible Immunophenotyping Results Across Experiments
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CT26 Tumor Cytokine Analysis by Cytometric Bead Array
Our Services
Powered Research is well known for rapid study turnaround, and our scientific experts allow for timely study scheduling and execution.
Our staff has extensive expertise in the design and development of non-GLP preclinical data packages, including tolerability and pharmacology models, drug distribution studies, and custom experimental designs.
AAALAC Accredited
Certified Excellence
Flexibility
Use our internal protocols or work with us to design your own.
Scalability
Our clients include small startups, large pharma companies, and biotech companies.
70 Domain Experts
A committed team of scientists, veterinarians, and technicians.
Satisfaction
97% of our clients place a second study with us in the first 6 months.
