PHARMACOLOGY

As a specialized leader in the development of ocular pharmacology models, Powered Research can help you to assess the efficacy of your drug product or device candidates. Pharmacology models can be used to differentiate between formulations, active pharmaceutical ingredients, or device iterations, enabling you to choose the most effective product to move forward in development. Powered Research offers more than 15 nonclinical animal efficacy models, each of which is specifically designed to assess the therapeutic efficacy in an ophthalmic disease state, condition, or surgical intervention. Our models are supported by our team of ophthalmic experts, as well as our collection of precise instrumentation, ensuring that our studies are conducted correctly and provide relevant data.

Models include:

Anterior Chamber Inflammation (paracentesis, corneal incision)
Laser Choroidal Neovascularization
Corneal Wound Healing (alkali, scrape, abrasion)
Corneal transplantation
Experimental Autoimmune and Endotoxin or MTB-Induced Uveitis
Oxygen-Induced Retinopathy
Sodium Iodate-Induced Retinal Degeneration
AAA-Induced Chronic Retinal Neovascularization
VEGF-Induced Retinal Leakage and Neovascularization
Phacoemulsification Surgery
Allergic Conjunctivitis
Normotensive IOP/Glaucoma
Light-induced Retinal Degeneration
NMDA Neuroprotection
Corneal Transplant
DMEK/DSEK Surgical model
Targeted Drug/Gene Therapy/Device Delivery (subretinal, IVT, IC, subconjunctival)
Specialized Surgical Models
Model Development