Oncology & Radiopharmaceutical Evaluation

We offer a full suite of services for evaluating potential cancer therapeutics, from experimental design and in vivo tumor modeling to extensive endpoint analyses. Our team is fully equipped to ensure start-to-finish characterization of your test agent on an expedited timeline.

Our Expert Leadership Team shares decades of drug development experience.

Our Capabilities

Rodent housing in a 20,000 sq ft
multi-species vivarium staffed by
highly trained technicians and
veterinarians
Human and murine cell culture in a
modern 2000 sq ft laboratory
Flexible and customized flow
panels for deep immune profiling
with our 5-laser Cytek® Aurora
spectral cytometer
Radiopharmaceutical candidate in vivo profiling
Evaluation of pharmacokinetics, biodistribution, and efficacy in rodent models
Test batch conjugation chemistry development
Broad isotope license

Full Spectrum Flow Cytometry

5-laser Cytek® Aurora flow
cytometer with automated sample
loader
Expansion beyond 18 color panels
and improved resolution of
subpopulations
Autofluorescence extraction
Pre-optimized and custom panel
options available
Panel qualification

All-in-one Service

Study design
Cell culture and implant
Test agent dosing via any route
Timed samplings and necropsy

Tissue Sectioning and Imaging

Start to Finish tissue processing:
Cell/organ/tumor collection and
fixation
Paraffin embedding and
cryopreservation
Sectioning and staining
Epifluorescence microscopy
Histological stains & antibodies for
diagnostic & marker-based analysis
Hematoxylin & eosin
Immune cell markers including but
not limited to: CD3, F4/80, CD4,
CD8, CD68
Endothelial markers: CD31 &
Isolectin I-B4
Many More!

Endpoint Data

Tumor volume and body weight
MTDs and Dose Range Finding
PK/PD
Immunophenotyping by flow cytometry
Cytokine analysis
H&E staining
Immunohistochemistry
Immunofluorescence
Image analysis

Other In-House Services Include

qPCR
ELISA
Western Blot
Immunohistochemistry
In-situ hybridization